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A new study looks at the role of genes and their differences in exercise results. Run Photo / Getty Images
  • Researchers at the University of Cambridge published a meta-analysis in PLOS A Identification of 13 candidate genes associated with fitness outcomes in previously untrained individuals.
  • Genetic influences accounted for 72% of the results in the strength training group.
  • Genetic factors had a lower impact on results in aerobic (44%) and anaerobic energy groups (10%).
  • More research is needed to find out the exact role of fitness genes and how exercise can be adapted to genetic makeup.

It is physical activity. Important To maintain health, reduce chronic diseases and prevent premature death. Of 2018 Exercise Guidelines for Americans They recommend moderate strength and vigorous aerobic exercise, along with exercises that strengthen the core muscle groups.

Of Advice For adults, 150-300 minutes of moderate vigorous aerobic exercise, 75-150 minutes of intense aerobic exercise or moderate exercise. You can distribute this activity throughout the week and participate in strength training at least 2 days a week to receive additional health benefits.

The three most important factors in determining health-related fitness are cardiovascular fitness, muscle strength and anaerobic strength. Cardiovascular or Cardiovascular fitness During exercise, the respiratory and circulatory systems measure how well they deliver oxygen to the skeletal muscles.

Of High oxygen content (VO2 max) Testing is one way to determine cardiovascular fitness. The VO2 Max test measures the body’s maximum oxygen consumption during strenuous exercise, such as running on a treadmill.

High VO2 Max demonstrates improved ability to supply and use oxygen and maintain aerobic activity for longer periods of time. Low cardiac output It is a prediction Cardiovascular disease and death in adults for all causes.

Muscle strength is the ability to exert sufficient force against external resistance to perform physical activity and maintain mobility.

Anaerobic activity involves the breakdown of glucose for energy without the use of oxygen. Anaerobic energy measures the strength of the body in a short period of time.

Increased heart rate, muscle strength, and anaerobic strength may improve a person’s overall fitness level, but the response to exercise varies greatly from individual to individual.

as if Session 22nd Annual Congress of the European College of Sports Science, Dr. Bernd Wolfter“The environment is a major factor,” said a professor of sports medicine at Humboldt University in Berlin. [for trainability], And now, we know that 25-40% of the phenotype variability is coming from genetic results, and 60-75% are coming from. [from] Environmental Impacts ”

Certain genes are called Candidate genes It can predict successful responses to targeted exercise types. These genes can affect energy pathways, metabolism, storage, and cell growth in the body.

These findings led researchers from the University of Raskkin University, UK, to conduct research in the field of sports and exercise science at Cambridge. Meta-analysis To identify a particular version, or alleles, Candidate genes associated with exercise response in untrained participants. The team analyzed strength, anaerobic strength, and cardiovascular fitness.

Individuals inherit one gene from each parent. The person is genetically homozygous if both allergens are the same and the other two are different.

The study also found that identified genes and other factors contributed to differences in exercise response among participants. The researchers analyzed the results of a total of 3,012 participants from 24 different studies. Of the group, 1,512 participants were male and 1,239 were female. Gender of the remaining 261 participants was not specified.

The average age of the participants was 28 years. There were 89 teams: 43 aerobics, 29 strength and 17 strength. The researchers identified 13 candidate genes and others, of which nine, six, and four were related to cardiovascular fitness, muscle strength, and anaerobic strength.

On average, participants in cardiovascular fitness studies received aerobic training for 36 minutes 3 days a week for a total of 12 weeks. It was strength. 77% maximum heart rate Or 74% VO2 high. The researchers found that a 44% difference in aerobic training response was due to genetic influences.

Strength training involves an average of 174 repetitions per 75% strength per session. One-frequency high. Sessions are held 3 days a week for a total of 10 weeks. Genes make up 72% of the differences in strength training.

Participants in the anaerobic power group had an average strength of 4-12 cycles – 90-110% VO2 max or 0.075 load per kilogram of weight – 3 days a week for 5 weeks. Genes had less of an effect on the energy group, with only 10% of the response variability due to genetic influences.

Dr. Bert MandelbaHe is a sports medicine specialist and orthopedic surgeon at the Cedars-Sinai Kerlan-Jobe Institute in Los Angeles and was not involved in the study. Medical news today “Genomics and Aspects […] Phenotypic and genotype expression […] Physical activity and exercise are now linked to a variety of genomic patterns.

“As we learn more [the] Phenotonic description of different types of haploids in genes, there [will] Be a spectrum of how we interpret these […] In the future – this is one of the most accurate studies. “

The strengths of this meta-analysis include evaluating study groups such as aerobic, strength, or strength and gene subgroups. Because the sample size of some genes is small in this review, further research is needed to determine the exact role of these genes in influencing cardio-pulmonary fitness, strength, and anaerobic energy.

The results of future research may, in theory, support the individuality and adaptation of exercise programs based on a person’s genetic makeup.

Henry C. Chung, lead author of the study and Ph.D. The researcher says:

“Because everyone’s genetic makeup is different, our body responds a little differently to the same exercises. Therefore, it is important to be able to improve the effectiveness of exercise by identifying a person’s genotype and developing a unique training program for them.